Векторы в генотерапии рака: преимущество спор клостридий перед вирусами (продолжение...)

64. Nuyts S, Van Mellaert L, Theys J, Landuyt W, Lambin P, Ann J: Clostridium spores for tumor-specific drug delivery. Anticancer Drugs 2002, 13(2):115-25.

65. Folkman J: What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 1990, 82:4-6.

66. Vaupel P, Mayer A: Hypoxia in cancer: significance and impact on clinical outcome. Cancer Metastasis Rev in press. 2007, Apr 18.

67. Hay JG: The potential impact of hypoxia on the success of oncolytic virotherapy. Curr Opin Mol Ther 2005, 7(4):353-8.

68. Janssen HL, Haustermans KM, Balm AJ, Begg AC: Hypoxia in head and neck cancer: how much, how important? Head Neck 2005, 27(7):622-38.

69. Agrawal N, Bettegowda C, Cheong I, et al.: Bacteriolytic therapy can generate a potent immune response against experimental tumors. Proc Nat Acad Sci 2004, 101:15172-15177.

70. Kasono K, Blackwell JL, Douglas JT, Dmitriev I, Strong TV, Reynolds P, Kropf DA, Carroll WR, Peters GE, Bucy RP, Curiel DT, Krasnykh V: Selective gene delivery to head and neck cancer cells via an integrin targeted adenoviral vector. Clin Cancer Res 1999, 5:2571-2579.

71. Huang Q, Zhang X, Wang H, Yan B, Kirkpatrick J, Dewhrist MW, Li CY: A novel conditionally replicative adenovirus vector targeting telomerase-positive tumor cells. Clin Cancer Res 2004, 10:1439-1445.

72. Marty C, Schwendener RA: Cytotoxic tumor targeting with scFv antibody-modified liposomes. Methods Mol Med 2005, 109:389-402.

73. Fox ME, Lemmon MJ, Mauchline ML, Davis TO, Giaccia AJ, Minton NP, Brown JM: Anaerobic bacteria as a delivery system for cancer gene therapy: in vitro activation of 5-fluorocytosine by genetically engineered clostridia. Gene Ther 1996,
3(2):173-8. Erratum in: Gene Ther 1996 Aug;3(8):741.

Подготовила Дарья Червякова

Источник - Интернет-журнал "Коммерческая Биотехнология"

Первоисточник Ming Q Wei, Ruimei Ren, David Good Jozef Ann. Clostridial spores as live 'Trojan horse' vectors for cancer gene therapy: comparison with viral delivery systems//Genetic Vaccines and Therapy, 2008, 6:8.

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